Ongoing EU Clinical Trials
ESVONC attaches great importance to innovation and evidence-based medicine in the field of veterinary oncology. Therefore, we are happy to share with you with a monthly overview of ongoing canine oncology trials in Europe. We are convinced that knowledge of these trials will enhance collaboration between researchers and clinicians, thus increasing recruitment for clinical trials and treatment options for dogs.
Please find below a non-exhaustive listing of ongoing trials as gathered in the Oncowaf database. For more details about these trials, please visit https://oncowaf.be/en/ClinicalTrials.
If you have an ongoing clinical trial and would like to add it to the Oncowaf clinical trial database and this mailing, please contact contact@oncowaf.com. This list is an intiative of dr. Laetitia Cicchelero (DVM, PhD, Cross-health coordinator @ Faculty of Veterinary Medicine, Ghent University). Laetitia is initiator and inspirer of ONCOWAF. ESVONC wishes to thank Laetitia for her efforts to create this useful overview.
This list is updated on a monthly basis.
(green: new trial, orange: trial enters its last month of recruitment).
Country | Requested tumour types for clinical trial | Type of trial | |
Belgium | Head & Neck tumours | Fluorescence-guided surgery | Hilde de Rooster Nayra Valle |
Osteosarcoma, chondrosarcoma, benign osteolytic lesions |
Percutaneous cementoplasty |
||
Transitional cell carcinoma - bladder | Characterisation of biomarkers and immune response to improve diagnosis, prognosis and treatment | ||
B cell lymphoma | Sample collection to study lymphoma and optimize its approach | ||
All tumour types | Cardiac ultrasound to explore the effects of chemotherapy on the heart (diagnostic trial) | Gitte Mampaey | |
All tumour types | Novel imaging system to improve intra-operative cancer margin assessment: Fluorescence Lifetime Imaging | Simone Jansen | |
France | Urothelial carcinoma | Focused ultrasound anti-cancer treatment at high intensity: evaluation of tolerance and efficacy | Gabriel Chamel |
Easily reachable carcinoma and/or liver carcinoma and/or carcinomic liver metastases | Immunotherapy | Telomium | |
Metastatic carcinoma | Assessing safety and efficacy of medical device capturing circulating tumour cells | OCRvet | |
Oral malignant melanoma, oral SCC | Intra-tumoral immunotherapy | VetAgro Sup | |
Italy | All tumour types | Aspartame for the prevention of chemotherapy-induced diarrhoea | Paola Valenti |
Portugal | Hepatic neoplasia | Thermoablation by microwaves or radiofrequency | Joaquim Henriques |
Chemodectoma | Microwave ablation | Joaquim Henriques |
|
Spain | All tumour types | Aspartame for the prevention of chemotherapy-induced diarrhoea | Juan Borrego |
B cell lymphoma | Evaluation of circulating tumour cells (diagnostic trial) | ||
Sweden |
Hematological cancers (lymphoma, leukemia) |
Treatment with a transcription inhibitor |
|
Switzerland | Sinonasal tumours | Heterogenous dose treatment radiotherapy | Carla Bley |
High-grade glioma | Chemoradiation for high-grade glioma | Carla Bley | |
Peripheral nerve sheath tumour of the brachial or lumbar plexus | Fluorescence-guided surgery | Mirja Nolff |
|
Soft tissue sarcoma | Fluorescence-guided surgery | Mirja Nolff | |
Soft tissue and bone sarcomas | Improve the detection and classification of sarcomas using new PET tracers | Mirja Nolff | |
The Netherlands | Metastatic or recurrent insulinoma | Prospective evaluation of palliative and adjuvant toceranib phosphate therapy | Floryne Buishand |
Pheochromocytoma | Study and sample collection of pheochromoctomas to allow development of therapy for inoperable tumours | Utrecht University | |
Histocytic sarcoma | Study and sample collection of Flatcoated retrievers to study histiocytic sarcoma and develop DNA test | Utrecht University | |
Osteosarcoma | Viral Therapy | Utrecht University | |
TCC of the bladder neck, prostate cancer | Cancer vaccine (immunotherapy) | Arno Roos Lobke van Bergen |
|
United Kingdom | Metastatic or recurrent insulinoma | Prospective evaluation of palliative and adjuvant toceranib phosphate therapy | Floryne Buishand |
All tumour types | Aspartame for the prevention of chemotherapy-induced diarrhoea | ||
Oral melanoma | Immunotherapy for dogs with oral melanoma – tigilanol tiglate | Kelly Blacklock | |
All tumour types | Validation of canine oncology-proxy reported outcome measure to support symptom management and quality of life in dogs undergoing chemotherapy | Aura Veterinary |
ESVONC does not endorse any of the clinical studies listed above, and expressly disclaims any responsibility or liability for any of the content related to these studies. The use of the ESVONC listing for the purpose of recruitment can, however, be acknowledged in the material and methods of these studies.