Ongoing EU Clinical Trials

ESVONC attaches great importance to innovation and evidence-based medicine in the field of veterinary oncology. Therefore, we are happy to share with you with a monthly overview of ongoing canine oncology trials in Europe. We are convinced that knowledge of these trials will enhance collaboration between researchers and clinicians, thus increasing recruitment for clinical trials and treatment options for dogs.

Please find below a non-exhaustive listing of ongoing trials as gathered in the Oncowaf database. For more details about these trials, please visit https://oncowaf.be/en/ClinicalTrials.

If you have an ongoing clinical trial and would like to add it to the Oncowaf clinical trial database and this mailing, please contact contact@oncowaf.com. This list is an intiative of dr. Laetitia Cicchelero (DVM, PhD, Cross-health coordinator @ Faculty of Veterinary Medicine, Ghent University). Laetitia is initiator and inspirer of ONCOWAF. ESVONC wishes to thank Laetitia for her efforts to create this useful overview.

This list is updated on a monthly basis.
(green: new trial, orange: trial enters its last month of recruitment).

Country Requested tumour types for clinical trial Type of trial  
Belgium Head & Neck tumours Fluorescence-guided surgery Hilde de Rooster hilde.derooster@ugent.be
Nayra Valle
nayra.valle@ugent.be
  Osteosarcoma, chondrosarcoma, benign osteolytic lesions Percutaneous cementoplasty Stella Minnoye
Stella.minnoye@anicura.be
  Transitional cell carcinoma - bladder Characterisation of biomarkers and immune response to improve diagnosis, prognosis and treatment Annick Hamaide
Annick.Hamaide@uliege.be
  B cell lymphoma Sample collection to study lymphoma and optimize its approach

Anna Blockeel
Anna.blockeel@ugent.be 

France Glioma Oral treatment Oncovet Clinical Research, Laurène Van Overbeke
lvanoverbeke@oncovet-clinical-research.com
  All tumours managed by a metronomic chemotherapy protocol Pharmacokinetic study of metronomic chemotherapy agents residues onco.chuvac@vetagro-sup.fr
  Urothelial carcinoma Focused ultrasound anti-cancer treatment at high intensity: evaluation of tolerance and efficacy gabriel.chamel@anicura.fr
  Easily reachable carcinoma and/or liver carcinoma and/or carcinomic liver metastases Immunotherapy telomium.biotech@gmail.com 
  Metastatic carcinoma Assessing safety and efficacy of medical device capturing circulating tumour cells mstricher@ocrvet.com
  Oral malignant melanoma, oral SCC  Intra-tumoral immunotherapy  onco.chuvac@vetagro-sup.fr
Italy All tumour types Aspartame for the prevention of chemotherapy-induced diarrhoea Paola Valenti paola.valenti@anicura.it
Portugal Hepatic neoplasia Thermoablation by microwaves or radiofrequency Joaquim Henriques joaquim.henriques@anicura.pt
  Chemodectoma Microwave ablation Joaquim Henriques joaquim.henriques@anicura.pt
Spain All tumour types Aspartame for the prevention of chemotherapy-induced diarrhoea Juan Borrego juan.borrego@ivcevidensia.es
  B cell lymphoma Evaluation of circulating tumour cells (diagnostic trial)

Victor Domingo Roa

info@atypia.es

Switzerland Sinonasal tumours Heterogenous dose treatment radiotherapy Carla Bley
onkologie@vetclinics.uzh.ch
  High-grade glioma Chemoradiation for high-grade glioma Carla Bley
onkologie@vetclinics.uzh.ch
  Oral tumours Fluorescence-guided surgery Mirja Nolff
mnolff@vetclinics.uzh.ch
  Peripheral nerve sheath tumour of the brachial or lumbar plexus Fluorescence-guided surgery Mirja Nolff
mnolff@vetclinics.uzh.ch
  Soft tissue sarcoma Fluorescence-guided surgery Mirja Nolff
mnolff@vetclinics.uzh.ch
  Soft tissue and bone sarcomas Improve the detection and classification of sarcomas using new PET tracers Mirja Nolff
mnolff@vetclinics.uzh.ch
The Netherlands Metastatic or recurrent insulinoma Prospective evaluation of palliative and adjuvant toceranib phosphate therapy Floryne Buishand
fbuishand@rvc.ac.uk
  Pheochromocytoma Study and sample collection of pheochromoctomas to allow development of therapy for inoperable tumours  bit.ly/3BEVnHk
  Histocytic sarcoma  Study and sample collection of Flatcoated retrievers to study histiocytic sarcoma and develop DNA test  bit.ly/3BI2v5H 
  Osteosarcoma Viral Therapy  bit.ly/3U7EJ9I 
  TCC of the bladder neck, prostate cancer  Cancer vaccine (immunotherapy)

Arno Roos oncologie@edz-nieuwegein.nl Lobke van Bergen oncologie@edz-barendrecht.nl

United Kingdom Metastatic or recurrent insulinoma Prospective evaluation of palliative and adjuvant toceranib phosphate therapy Floryne Buishand
fbuishand@rvc.ac.uk
  All tumour types Aspartame for the prevention of chemotherapy-induced diarrhoea Aura Veterinary
hello@auravet.com
University of Edinburgh
HFSAreception@ed.ac.uk
  Oral melanoma Immunotherapy for dogs with oral melanoma – tigilanol tiglate

Kelly Blacklock
kelly.blacklock@ed.ac.uk


ESVONC does not endorse any of the clinical studies listed above, and expressly disclaims any responsibility or liability for any of the content related to these studies. The use of the ESVONC listing for the purpose of recruitment can, however, be acknowledged in the material and methods of these studies.